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What is the biology underlying the condition of lupus? How could the symptoms of lupus be lessened on the cellular level?

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Neutrophil extracellular traps, or NETs,...

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Opsonization is a process whereby the innate and adaptive immune mechanisms work together


A) to phagocytize an invader.
B) to activate complement proteins.
C) for antibody secretion.
D) to destroy cancer cells.
E) during apoptosis.

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The primary lymphoid organ(s) is/are the


A) adenoids.
B) appendix.
C) Peyer's patches.
D) thymus.
E) tonsils.

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Why can acne be treated with antibiotics?

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Acne is treated with antibiotics because...

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How is it that Gram-positive cells are more resistant to complement than Gram-negative cells?

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The lipopolysaccharide of outer cell mem...

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Which of the following two organisms are commonly used as probiotics?


A) Streptococcus mutans and Lactobacillus acidophilus
B) Bacteroides and Lactobacillus acidophilus
C) Enterococcus and Enterobacter species
D) Bifidobacterium and Lactobacillus acidophilus
E) Diphtheroids and Fusobacterium species

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Which of the following would NOT result in an increase in natural killer cells?


A) internal parasite
B) herpes virus
C) Neisseria gonorrhoeae
D) bacterial infection
E) cancer

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Why is it important for people with mitral valve prolapse to take antibiotics prior to a dental exam or procedure?

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During a dental procedure, organisms tha...

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How is it that Clostrioides difficile, often a part of the normal intestinal microflora, can be the causative agent of pseudomembranous enterocolitis?

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When a person takes antibiotics, normal ...

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Which of the following is/are Type I interferon?


A) NOD-receptors
B) TLR4
C) IFN-beta
D) IFN-gamma
E) cytokines

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Which of the following is an example of a semi-specific, innate immune mechanism associated with mucosal surfaces?


A) Secretory IgA prevents adhesion to mucosal surface.
B) Extravasation of neutrophils is triggered by specific signals.
C) Interferons produced by the host will act on specific viruses in the mucosa.
D) Toll-like receptors on the host bind a specific microbe-associated molecular pattern, or MAMP.
E) The type of inflammation mounted varies with pathogen.

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Extravasation is the process by which ________ move(s) from the bloodstream into surrounding tissues.


A) neutrophils
B) natural killer cells
C) antibodies
D) interferons
E) complement

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How can differences in gut microbiota account for obesity and leanness in humans?

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About 15%-20% of the human caloric intak...

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Microbes in and on humans sharpen immunity and protect from infection. Explain why these benefits also come with considerable risk.

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The microbiota of humans are extremely b...

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A man has been taking excessive amounts of antacids for heartburn. These tablets are very alkaline. Which innate defense mechanism might be altered by his actions?


A) mucociliary elevator
B) lysozyme
C) pH of stomach
D) flushing action of urine
E) skin pH

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C-reactive protein is an acute-phase reactant that will bind to components of


A) IL-1.
B) TNF-alpha.
C) bacterial cell surfaces.
D) host cell membranes.
E) cytokines.

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Interferons are


A) antibacterial agents produced by skin, GI-tract, and lung cells.
B) secreted by eukaryotic cells in response to intracellular infection.
C) only produced by activated phagocytes.
D) host specific and virus specific.
E) able to block bacterial replication.

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Which part of the physical defense system uses skin-associated lymphoid tissue (SALT) ?


A) gastrointestinal tract
B) lungs
C) skin
D) mucus membranes
E) defensins

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A woman falls and suffers a cut on her leg. The cut went through her skin and she is bleeding. Which of the following defense mechanisms will participate in eliminating microbes contaminating the cut?


A) mucociliary elevator
B) normal skin flora
C) acidic skin secretions
D) lysozyme
E) phagocytosis and the inflammatory response

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Explain the steps of the basic inflammatory response as pictured in the figure below. Explain the steps of the basic inflammatory response as pictured in the figure below.

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Infection occurs via a splinter. Residen...

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