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You have a 12-year-old patient who is hoping to be a professional basketball player.As part of her dream,she is hoping to grow as much as possible before her growth plates fuse.As her doctor,you recommend which of the following to help her grow?


A) Always getting a good night's sleep
B) Frequent exercise
C) Drinking lots of water
D) Eating twice as much protein as is recommended for a person her size
E) None of these will help her grow

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A general name for a hormone that regulates mineral ion homeostasis is "tropic hormone."

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What is a main difference between the modes of action of peptide hormones and steroid hormones?


A) Peptide hormones bind to intracellular receptors,whereas steroid hormones bind to receptors on the cell surface.
B) Peptide hormones act as second messengers,whereas steroid hormones bind to receptors in the cytosol.
C) Peptide hormones bind to receptors on the cell surface,whereas steroid hormones act as second messengers.
D) Peptide hormones bind to receptors on the cell surface,whereas steroid hormones bind to intracellular receptors.
E) There are no differences;both act by binding to intracellular receptors.

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Unlike neurons,endocrine cells generally do not act as integrators of various kinds of positive or negative inputs.

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An endocrine cell that contains an abundance of rough endoplasmic reticulum,a large Golgi apparatus,and many secretory granules is likely to secrete a peptide hormone.

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You have discovered a novel steroid hormone.You'd like to isolate its receptor as part of your next project.Where should you look first?


A) On the cell surface
B) In the blood stream
C) In the cytoplasm
D) Any of these might be places where the receptor could be found.

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Which does NOT apply to hormones?


A) They are chemical regulators that are conveyed from one organ to another via the bloodstream.
B) In some cases,the same chemical substances can also function as local regulators and/or neurotransmitters.
C) All hormones are derived from cholesterol.
D) They are secreted into the blood by ductless glands.
E) They are sometimes secreted by neural tissue.

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Which is NOT an effect of parathyroid hormone?


A) Increases the bone-degrading activity of osteoclasts
B) Decreases reabsorption of calcium by the kidneys
C) Promotes vitamin D synthesis,leading to increased intestinal absorption of calcium
D) Increases plasma [Ca²⁺] 
E) Decreases reabsorption of phosphate by the kidneys

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The receptors for estradiol,T₃,and vasopressin are all located in the nuclei of target cells.

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Deficiency of iodine in the diet results in ________ caused by ________.


A) a goiter;increased production of thyroid-stimulating hormone (TSH) and increased thyroid hormone levels
B) atrophy of the thyroid gland;loss of negative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
C) a goiter;loss of negative feedback by thyroid hormones and increased thyroid-stimulating hormone (TSH) levels
D) atrophy of the thyroid gland;decreased sensitivity of receptors for thyroid-stimulating hormone (TSH)
E) atrophy of the anterior pituitary gland;loss of negative feedback by thyroid hormones

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During a long illness,Terrell has not been eating much.As a result,his plasma Ca²⁺ levels decrease.Which hormone would we expect to see in higher levels than usual in his blood?


A) Thyroxine
B) Parathyroid hormone
C) Calcitonin
D) Growth hormone
E) Insulin

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Which is most likely a characteristic of cells that secrete steroid hormones?


A) They store large amounts of hormone.
B) They are characterized by abundant smooth endoplasmic reticulum and few secretory granules.
C) They contain large numbers of secretory granules.
D) They are found in the anterior pituitary gland.
E) They are found in the medulla of the adrenal gland.

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Some women (including Angelina Jolie)with mutations in tumor suppressor genes,opt for oophorectomy (removal of their ovaries)to decrease their risk of some types of cancer.Unless they take supplements,they probably will have lower circulating levels of both androgens and estrogen.

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In order for growth to occur,the overall rate of anabolism must be greater than the overall rate of catabolism.

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You have discovered a novel hormone.Early experiments have shown that it is quite hydrophobic.Which of the following is likely to also be TRUE of these hormones?


A) They mostly bind to receptor proteins in the surface membrane of target cells.
B) They are generally polar molecules.
C) They usually have very rapid effects on target cells.
D) Their mechanism of action generally involves altering protein synthesis.
E) They are highly soluble in blood plasma.

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The liver is a target gland of growth hormone.

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Depressed levels of thyroid hormones in blood resulting from a defect in the cells that secrete TSH is an example of primary hyposecretion of thyroid hormones.

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Stimuli for the secretion of hormones include changes in plasma concentrations of ions,nutrients,and other hormones.

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A precursor of cortisol is cholesterol.

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Which of the following statements about hormones is correct?


A) Anterior pituitary hormones are synthesized in the hypothalamus.
B) All hormones secreted by the anterior and posterior pituitary glands are peptides.
C) IGF-1 stimulates growth by increasing growth hormone secretion through positive feedback.
D) All of the hypophysiotropic hormones are peptides.
E) Only steroid hormones can regulate the secretion of steroid hormones.

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