Question 1

The secondary response to an antigen is more rapid and robust than the primary response.

Accepted Answer

A) True 
 B)False

Question 2

You have received the first hepatitis A vaccine.It was required for your mission trip to Nicaragua in Central America, where hepatitis A is common.However, you never went back for the booster shot of the vaccine, which should have been received within 6 months of the initial vaccination.What statement accurately reflects your present immunity to this pathogen?

Accepted Answer

A)  You are at risk to get hepatitis A since your immune status is only partial.Not enough immune memory cells were produced since you received one dosage of vaccine, so you are likely to get the disease when exposed to the virus.
B)  The one dosage is not enough because it only activated humoral immunity.The second dosage is used to activate cell-mediated immunity.The combination of the two immune responses gives you 100% coverage of immunity to hepatitis A.
C)  This is not a problem because the second dosage is just extra protection.Your immune status would be very high.
D)  Not a problem because at any time, in a year, 5 years, etc., you can go get the booster vaccine for hepatitis A and be fully covered by immunity.

Question 3

Properties of effective antigens include all of the following except

Accepted Answer

A)  they are foreign to the immune system.
B)  they have molecular complexity.
C)  they are large molecules with a minimum molecular weight of 1,000.
D)  they are large polymers made up of repeating subunits.
E)  they are cells or large, complex molecules.

Question 4

Edward Jenner's work involved

Accepted Answer

A)  development of passive immunotherapy.
B)  immunization using a related, less pathogenic organism to give protection against a more pathogenic one.
C)  development of an immunization to protect people against cowpox.
D)  inoculation of dried pus from smallpox pustules into a person to stimulate immunity.

Question 5

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one epitope.

Accepted Answer

A)  variable
B)  Fc
C)  hinge
D)  FAb
E)  terminal

Question 6

Which lymphocytes lack specificity for antigen and attack cancer cells and virus-infected cells?

Accepted Answer

A)  Delayed hypersensitivity T cells
B)  Natural killer (NK)  cells
C)  Suppressor T cells
D)  Helper T cells
E)  Cytotoxic T cells

Question 7

A cytotoxic T lymphocyte, having been activated against a particular viral antigen, "sees" this same antigen displayed on the surface of a host cell.What will happen?

Accepted Answer

A)  The cytotoxic T cell will produce proteins that cause the host body cell to die.
B)  The cytotoxic body cell will activate B cells which then produce antibody against the antigen.
C)  The antigen will move inside of the host body cell, thereby hiding from the cytotoxic T cell.
D)  The cytotoxic T cell will produce antibodies against the antigen.

Question 8

The histocompatibility complex proteins function in

Accepted Answer

A)  antibody proliferation.
B)  T cell maturation.
C)  recognition of self.
D)  B cell maturation.

Question 9

B cell receptors differ from T cell receptors in that

Accepted Answer

A)  B cell receptors are comprised of four polypeptides, whereas T cell receptors have only two polypeptides in their quaternary structure.
B)  B cell receptors have two antigen binding sites, whereas T cell receptors have only one antigen binding site.
C)  B cell receptors are immunoglobulin in nature, whereas T cell receptors are not immunoglobulin molecules.
D)  B cell receptor immunoglobulins can be secreted as antibodies, whereas T cell receptors are never secreted.
E)  All of the choices represent differences between B cell and T cell receptors.

Question 10

Which is incorrect about the Fc region of an immunoglobulin?

Accepted Answer

A)  It contains an effector molecule that can bind to cells such as macrophages and mast cells.
B)  It forms the antigen binding sites.
C)  It determines the class to which the immunoglobulin belongs.
D)  It contains an effector molecule that can fix complement.
E)  It is called the crystallizable fragment.

Question 11

Which of the following statements does not represent the role of a cell marker in the third line of defense?

Accepted Answer

A)  They serve as transcription factors to initiate antibody production.
B)  They serve as recognition factors for self and nonself molecules.
C)  They are attachment sites for foreign molecules.
D)  They receive and transmit signals to coordinate the immune response.

Question 12

Superantigens are

Accepted Answer

A)  body tissues that the immune system mistakes as foreign.
B)  cell markers found in some member of a species but not in other members.
C)  bacterial toxins that activate T cells at a 100 times greater rate than other antigens.
D)  antigens that evoke allergic reactions.

Question 13

The ability of TC cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce __________ and __________; proteins that punch holes in the target cell membrane.

Accepted Answer

A)  interleukin-1; interleukin-2
B)  perforin; granzyme
C)  interferon; interleukins
D)  antibodies; interferons

Question 14

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Accepted Answer

A) True 
 B)False

Question 15

Antigens that elicit allergic reactions are called ______.

Accepted Answer

A)  allergens
B)  autoantigens
C)  superantigens
D)  heterophilic antigens

Question 16

One plasma cell will secrete antibodies of various classes, but the antibodies will all have the same specificity.

Accepted Answer

A) True 
 B)False

Question 17

Cytotoxic T cells

Accepted Answer

A)  secrete interleukin-2 to stimulate B and T cells.
B)  lack specificity for antigen.
C)  secrete granzymes and perforins that damage target cells.
D)  are activated by free, soluble antigens.

Question 18

Which of the statements below represents the correct order of events in the adaptive immune response?

Accepted Answer

A)  Lymphocyte challenge, antigen presentation, lymphocyte development, lymphocyte response
B)  Antigen presentation, lymphocyte development, lymphocyte challenge, lymphocyte response
C)  Antigen presentation, lymphocyte challenge, lymphocyte development, lymphocyte response
D)  Lymphocyte development, antigen presentation, lymphocyte challenge, lymphocyte response

Question 19

The embryonic yolk sac, the liver, and the bone marrow are sites where

Accepted Answer

A)  T lymphocytes complete maturation.
B)  immune responses to antigen occur.
C)  stem cells give rise to immature lymphocytes.
D)  antigen is filtered from the blood.
E)  antigen is filtered from tissue fluid.

Question 20

MHC molecules are found on all of the following cells except ______.

Accepted Answer

A)  red blood cells
B)  epithelial cells
C)  eosinophils
D)  islet of Langerhans cells
E)  leukocytes

Exam 15: Host Defenses II: Specific Immunity and Immunization

Properties of effective antigens include all of the following except

Correct Answer
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Which is incorrect about the Fc region of an immunoglobulin?

Correct Answer
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Cytotoxic T cells

Correct Answer
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Superantigens are

Correct Answer
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The histocompatibility complex proteins function in

Correct Answer
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Which of the statements below represents the correct order of events in the adaptive immune response?

Correct Answer
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MHC molecules are found on all of the following cells except ______.

Correct Answer
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The ability of T_C cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce and ; proteins that punch holes in the target cell membrane.

Correct Answer
verified

Which lymphocytes lack specificity for antigen and attack cancer cells and virus-infected cells?

Correct Answer
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B cell receptors differ from T cell receptors in that

Correct Answer
verified

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Correct Answer
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Edward Jenner's work involved

Correct Answer
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Which of the following statements does not represent the role of a cell marker in the third line of defense?

Correct Answer
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Correct Answer
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One plasma cell will secrete antibodies of various classes, but the antibodies will all have the same specificity.

Correct Answer
verified

Antigens that elicit allergic reactions are called ______.

Correct Answer
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A cytotoxic T lymphocyte, having been activated against a particular viral antigen, "sees" this same antigen displayed on the surface of a host cell.What will happen?

Correct Answer
verified

The secondary response to an antigen is more rapid and robust than the primary response.

Correct Answer
verified

The embryonic yolk sac, the liver, and the bone marrow are sites where

Correct Answer
verified

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one epitope.

Correct Answer
verified

Exam 15: Host Defenses II: Specific Immunity and Immunization

Properties of effective antigens include all of the following except

Correct AnswerverifiedShow Answer

Which is incorrect about the Fc region of an immunoglobulin?

Correct AnswerverifiedShow Answer

Cytotoxic T cells

Correct AnswerverifiedShow Answer

Superantigens are

Correct AnswerverifiedShow Answer

The histocompatibility complex proteins function in

Correct AnswerverifiedShow Answer

Which of the statements below represents the correct order of events in the adaptive immune response?

Correct AnswerverifiedShow Answer

MHC molecules are found on all of the following cells except ______.

Correct AnswerverifiedShow Answer

The ability of TC cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce __________ and __________; proteins that punch holes in the target cell membrane.

Correct AnswerverifiedShow Answer

Which lymphocytes lack specificity for antigen and attack cancer cells and virus-infected cells?

Correct AnswerverifiedShow Answer

B cell receptors differ from T cell receptors in that

Correct AnswerverifiedShow Answer

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

Correct AnswerverifiedShow Answer

Edward Jenner's work involved

Correct AnswerverifiedShow Answer

Which of the following statements does not represent the role of a cell marker in the third line of defense?

Correct AnswerverifiedShow Answer

Correct AnswerverifiedShow Answer

One plasma cell will secrete antibodies of various classes, but the antibodies will all have the same specificity.

Correct AnswerverifiedShow Answer

Antigens that elicit allergic reactions are called ______.

Correct AnswerverifiedShow Answer

A cytotoxic T lymphocyte, having been activated against a particular viral antigen, "sees" this same antigen displayed on the surface of a host cell.What will happen?

Correct AnswerverifiedShow Answer

The secondary response to an antigen is more rapid and robust than the primary response.

Correct AnswerverifiedShow Answer

The embryonic yolk sac, the liver, and the bone marrow are sites where

Correct AnswerverifiedShow Answer

Each _____ fragment of an antibody molecule contains the variable regions of a heavy and light chain that folds into a groove for one epitope.

Correct AnswerverifiedShow Answer

Correct Answer
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Correct Answer
verified

The ability of T_C cells to initiate apoptosis in virally-infected cells and cancer cells is dependent on their ability to produce and ; proteins that punch holes in the target cell membrane.

Correct Answer
verified

Correct Answer
verified

Correct Answer
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Correct Answer
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Correct Answer
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Correct Answer
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