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Typically,adhesins


A) are found on pili.
B) help bacteria attach to host cells.
C) are proteins.
D) are found on host cells.
E) are found on pili,help bacteria attach to host cells,AND are proteins.

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Which of the following would be considered a sign of a disease?


A) Headache
B) Pain
C) Nausea
D) Fever of 39 ∘\circ C

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The number of organisms necessary to insure infection is termed the


A) infectious dose.
B) fatal number.
C) minimum lethal dose.
D) pathogenic number.

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Virulent pathogens are


A) more likely to cause disease.
B) more likely to cause severe disease.
C) unable to cause disease.
D) more likely to be opportunists.

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Opportunists or opportunistic pathogens


A) are usually saprophytes.
B) take advantage of special circumstances.
C) are usually mutualistic.
D) always cause disease.

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People who carry and may spread pathogenic organisms without any overt symptoms of illness are called


A) primary infections.
B) secondary infections.
C) mutualists.
D) carriers.

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In two of Koch's postulates (#2 and #3) ,a pure culture of the organism is required.Which of the following would NOT be a possible consequence of using a contaminated culture?


A) You can't necessarily attribute the illness directly to the microbe in question-it may in fact be caused by the contaminating microbe.
B) There's the possibility that the test animal might be acutely susceptible to the contaminating microbe,but completely resistant to the microbe you suspect causes the illness of interest.As such,when you introduce it into the test animal,it could confuse your final results.
C) The problem is that one microbe may be toxic to the other.It may have killed all of your suspect microbe in the culture.Therefore,you can't be sure that you're infecting your test animals with the microbe you suspect is causing the illness,or if it's only the second (contaminating) microbe.
D) Even though there's a contaminating microbe present,so long as the original suspect microbe is also present,the disease should still manifest in test animals.It should also still be recoverable from test animals following infection.As such,there's really no consequence to using a contaminated culture.

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The normal microbiota provides protection against potentially harmful organisms and stimulates the immune system.Why would the immune responses to members of the normal microbiota cross-react with pathogens?


A) Because one person's normal microbiota is another person's pathogen-when we pick up "normal" microbes from a different person,they will always cause infection within us.
B) Because pathogens are oftentimes more virulent strains of our own normal microbial microbiota,so they will "look" roughly the same to our immune system (and be acted upon by our immune responses) .
C) Because the normal microbiota keeps the adaptive immune responses tuned up,active,and ready to respond to broad,general categories of microbes (i.e.,Gram-positive vs.Gram-negative microbes,viruses,etc.) .
D) Because the immune system is a "use it or lose it" system.If it isn't used on a regular basis,we completely lose the ability to respond to pathogens.The normal microbiota keeps the system going so that it can be ready to respond to such pathogens when we're exposed to them.

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A relationship in which one partner benefits and the other is harmed is termed


A) commensalism.
B) parasitism.
C) independence.
D) mutualism.

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Growth of a parasitic organism in or on the host is referred to as


A) colonization.
B) infection.
C) pathogenism.
D) mutualism.

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The series of steps used to connect an organism to a disease are known as


A) Pasteur's postulates.
B) Lister's aseptics.
C) Linnaeus taxonomics.
D) Koch's postulates.

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Infection always leads to disease.

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Newborn babies acquire microbiota by


A) passing through the birth canal.
B) breastfeeding.
C) contact with mother's skin.
D) environment.
E) All of the above are a source of microbiota.

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The damage caused by parasites may be due to


A) competition for nutrients.
B) the physical blocking of organs.
C) the direct digestion of host tissue.
D) the host's immune response.
E) All of the choices are correct.

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Which of the following factors is not considered important for the establishment of an infection?


A) Adherence
B) Dose
C) Toxicity
D) Virulence factors

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The connection between a particular organism and a specific disease was first made by


A) Jenner.
B) Pasteur.
C) Koch.
D) Leeuwenhoek.

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The spread of toxin via circulation is called


A) septicemia.
B) bacteremia.
C) sepsis.
D) toxemia.

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A relationship in which one partner benefits and the other is unaffected is termed


A) commensalism.
B) parasitism.
C) independence.
D) mutualism.

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Obligate intracellular parasites may be grown in special synthetic media.

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The composition of the normal microbiota may be affected by


A) hormonal changes.
B) use of antibiotics.
C) obesity level.
D) diet.
E) All of the choices are correct.

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