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Exam 3: Protein I: Composition and Structure

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Question 81

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The primary sequence of proteins is best described by the statement that proteins

A) contain amino acids.
B) include all the nitrogen compounds of tissues.
C) are salts of amino acids linked with one another.
D) are polymers formed by hydrogen bonding between the amino acids.
E) are polymers formed by amide linkages between the carboxyl and alpha-amino groups of alpha-amino acids.

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Question 82

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Which of the following is a characteristic of the amino acid composition of a protein which has an isoelectric pH (pI) of 9.5 ?

A) no basic amino acids
B) no acidic amino acids
C) no neutral amino acids
D) more basic than acidic amino acids
E) more acidic than basic amino acids

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Question 83

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Which of the following statements describing the alpha_helix is NOT correct?

Chaperone proteins help nascent proteins achieve correct folding. What other function do they serve?

Which of the following is a kind of physical/chemical interaction of major quantitative importance in the overall structure of most globular proteins and occurs chiefly in the interior areas of the molecule?

Proteins will normally exhibit minimum solubility in aqueous solutions at

We have treated a protein with chymotrypsin (cleaves at aromatic amino acid residues) and have isolated a polypeptide fragment produced during the chymotryptic digestion. The amino acid composition of the polypeptide was found to be amino acid moles/mole polypeptide lysine (lys) 2 glycine (gly) 1 serine (ser) 1 phenylalanine (phe) 1. The N-terminal amino acid, determined by the dansylation procedure, was serine. Treatment of the polypeptide with trypsin (cleaves at basic amino acid residues) gave two dipeptides plus free phenylalanine What is the amino acid sequence of this polypeptide?

All of the following statements about protein structure are correct EXCEPT which one?

Which of the following describes the side chain of phenylalanine?

A major force that contributes to the conformation of proteins and, in globular proteins, occurs primarily in their interior is

Collagen is a protein whose conformation is characterized by

All of the following bond types are significant for the maintenance of the secondary, tertiary, and quaternary structure of enzymes or proteins EXCEPT

Which of the following describes the side chain of leucine?

Denaturation of a protein usually involves the disruption of all of the following types of interactions EXCEPT

If gly has a positive charge in a buffer at pH 1, then gly-gly-gly in the same buffer should have which of the following charges?

Which of the following amino acids possesses an uncharged side-chain at pH 7.0?

Which of the following peptides would be partially hydrolyzed by the enzyme trypsin?

All of the following amino acids are required as precursors for collagen synthesis EXCEPT

Which of the following statements about protein structure is correct?

The peptide bond has all of the following characteristics EXCEPT